Chronic neck& back pain

Hi, I am 54 years old retired 2012 and not been able to commit to any activities or vacation or anything really. Friends seem to understand but spouse & family does not.Having trouble with that. Been through every test,blood,MRI's facet blocks,epidurals,acupuncture,Chiropractor,Naprapath,physical therapy.How do you cope with this without the anxiety,guilt and depression when you do not get any real clear diagnosis except muscle skeletal.